rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
1979-3-13
|
pubmed:abstractText |
The effect of 1.4% polyvinyl alcohol and castor oil vehicles on pilocarpine-induced hypotension was studied in 50 patients with open-angle glaucoma. Diurnal tension curves showed that the mean intraocular pressure was lower and the maximum diurnal variation smaller during the treatment with oily drops of 2% and 4% pilocarpine instilled 2-3 times daily than when 2% and 4% pilocarpine in polyvinyl alcohol was instilled 3-4 times daily. The differences were statistically significant. In long-term treatment no marked pilocarpine tolerance developed in cases treated with oily drops of pilocarpine. It is concluded that in the treatment of patients with open-angle glaucoma, the hypotensive effect of pilocarpine in an oily vehicle instilled 2-3 times daily is greater and more even than that of pilocarpine of corresponding strength in polyvinyl alcohol administered 3-4 times daily.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0001-639X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
56
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
489-95
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:735763-Adult,
pubmed-meshheading:735763-Aged,
pubmed-meshheading:735763-Castor Oil,
pubmed-meshheading:735763-Depression, Chemical,
pubmed-meshheading:735763-Drug Administration Schedule,
pubmed-meshheading:735763-Female,
pubmed-meshheading:735763-Glaucoma,
pubmed-meshheading:735763-Humans,
pubmed-meshheading:735763-Intraocular Pressure,
pubmed-meshheading:735763-Male,
pubmed-meshheading:735763-Middle Aged,
pubmed-meshheading:735763-Miotics,
pubmed-meshheading:735763-Ophthalmic Solutions,
pubmed-meshheading:735763-Pharmaceutical Vehicles,
pubmed-meshheading:735763-Pilocarpine,
pubmed-meshheading:735763-Polyvinyl Alcohol
|
pubmed:year |
1978
|
pubmed:articleTitle |
Effect of vehicle on pilocarpine-induced ocular hypotension.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|