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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1980-5-23
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pubmed:abstractText |
Serial serum carcinoembryonic antigen (CEA) assays were performed in 148 patients after potentially curative surgery for colorectal cancer. Thirty-seven patients developed proved recurrent tumour in a follow-up period of 2-5 years. Elevated CEA levels were recorded in 36 of these patients and in 27 rising levels preceded clinical symptoms of recurrent tumour. Two distinct patterns of CEA rise were observed: a 'fast' rise in which serum concentrations reached 100 microgram/l within 6 months of the first elevation and a 'slow' rise in which concentrations remained less than 75 microgram/l for at least 12 months. The majority of patients with the 'fast' rise had metastatic spread, whereas most patients with a 'slow' rise had local recurrence alone. This differential pattern may help to predict the site of recurrent tumour.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0007-1323
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
46-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7357243-Adenocarcinoma,
pubmed-meshheading:7357243-Carcinoembryonic Antigen,
pubmed-meshheading:7357243-Colonic Neoplasms,
pubmed-meshheading:7357243-Follow-Up Studies,
pubmed-meshheading:7357243-Humans,
pubmed-meshheading:7357243-Neoplasm Metastasis,
pubmed-meshheading:7357243-Neoplasm Recurrence, Local,
pubmed-meshheading:7357243-Postoperative Period,
pubmed-meshheading:7357243-Prognosis,
pubmed-meshheading:7357243-Rectal Neoplasms
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pubmed:year |
1980
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pubmed:articleTitle |
The clinical significance of the pattern of elevated serum carcinoembryonic antigen (CEA) levels in recurrent colorectal cancer.
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pubmed:publicationType |
Journal Article
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