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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1980-3-27
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pubmed:abstractText |
Fc epsilon R-bearing lymphocytes were induced in vitro by the culture of peripheral lymphocytes from ragweed-sensitive patients with antigen E together with, or followed by, human IgE. Neither antigen E alone nor IgE alone induced Fc epsilon R(+) cells. As expected, culture of normal lymphocytes with the antigen and IgE failed to increase Fc epsilon R(+) cells. However, mixed lymphocyte cultures from two normal individuals responsed to human IgE for the induction of Fc epsilon R(+) cells. In both antigen-stimulated and mixed lymphocyte cultures, a portion of Fc epsilon R(+) cells induced in vitro were T lymphocytes. Evidence was obtained that Fc gamma R(+) cells are involved in the induction of Fc epsilon R(+) cells. Depletion of Fc gamma R(+) cells in the lymphocytes from ragweed-sensitive patients, before culture with antigen E and IgE, abolished the ability of the lymphocytes to respond to IgE for an increase in Fc epsilon R(+) cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-1767
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
124
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
934-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7356720-DNA,
pubmed-meshheading:7356720-Humans,
pubmed-meshheading:7356720-Hypersensitivity, Immediate,
pubmed-meshheading:7356720-Immunoglobulin E,
pubmed-meshheading:7356720-Lymphocytes,
pubmed-meshheading:7356720-Receptors, Antigen, B-Cell,
pubmed-meshheading:7356720-Receptors, Fc,
pubmed-meshheading:7356720-Rosette Formation
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pubmed:year |
1980
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pubmed:articleTitle |
Induction of Fc epsilon-receptor bearing cells in vitro in human peripheral lymphocytes.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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