Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5747
pubmed:dateCreated
1980-4-17
pubmed:abstractText
Natural surveillance against malignant cells has been ascribed to so-called natural killer (NK) cells. These cells attack tumour cells without prior antigen stimulation and may also be cytotoxic to non-malignant cells. NK cells are routinely demonstrated by their cytotoxic activity against various types of tumour cell in vitro, but elucidation of the characteristics of the cytotoxic cells has hitherto been hampered by the lack of techniques by which NK cells can be isolated. Here we demonstrate murine NK-like activity from bone marrow cells cloned in semi-solid agar medium for granulocyte-macrophage colony formation. Data obtained indicate that such procedures considerably improve the possibility of obtaining quite pure NK cell populations by which the NK cell phenomenon may be studied in more detail.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0028-0836
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
283
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
578-80
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Autoreactive natural killer-like cells from agar-cloned murine bone marrow cells.
pubmed:publicationType
Journal Article