Linked Life Data

7353734

Source:http://linkedlifedata.com/resource/pubmed/id/7353734

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1980-4-23
pubmed:abstractText
Inhibition of gastric acid secretion by the combined use of cimetidine and pirenzepin has been studied in 5 cases of Zollinger-Ellison syndrome. In 4 acute cases i.v. cimetidine and i.m. pirenzepin were administered together as a treatment and were successful in 3 out of the 4 cases as judged by the disappearance of clinical symptoms and healing of the gastroduodenal and jejunal mucosal ulcerations. Secretory measurements indicated that addition of pirenzepin to cimetidine resulted in larger and more prolonged inhibition of acid secretion in these patients. The continuous record of intragastric pH in the 5th patient, over 24-hour periods, confirmed the above findings. Despite the use of large doses of pirenzepin, no significant side effects were noticed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0012-2823
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
56-61
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Interest of a combined antisecretory treatment, cimetidine and pirenzepin, in the management of severe forms of Zollinger-Ellison syndrome.
pubmed:publicationType
Journal Article, Case Reports