Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1980-4-23
pubmed:abstractText
Surface features of 19 stenotic aortic valves from patients undergoing valve replacement were investigated by scanning electron microscopy. Villi, prominent on five valves, were distributed either singularly or in clusters and differed in shape. Endothelial cells had microvilli and bulbous surface projections. Endothelial disruption with a focal loss of endothelial cells was uniformly observed. Erythrocytes were found scattered over the exposed subendothelial surface or enmeshed within fibrin networks on 11 of the valves. Activated leukocytes were seen on four valves and showed veil-like projections as well as microvilli. Platelets, observed on three valves, displayed pseudopodial formation and hyalomeric spreading, signifying an increased degree of membrane response. Most platelet aggregates were composed entirely of dendritic forms (reversible aggregates), but a few also contained spread forms (irreversible aggreates). Focal deposits of crystalline material, presumably containing calcium, were observed in areas of endocardial disruption.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0009-7322
pubmed:author
pubmed:issnType
Print
pubmed:volume
61
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
496-502
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Surface topography of stenotic aortic valves by scanning electron microscopy.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.