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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
|
pubmed:dateCreated |
1983-4-7
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pubmed:abstractText |
A significant number of normal and chronically anxious subjects were able to discriminate subjectively between a session in which they received naloxone and one which they received a placebo. However, affective and physiological measures did not differ significantly between the drug and placebo sessions. The weakness of the response makes it unlikely that a naloxone-responsive endogenous opioid system is substantially involved in the regulation of anxiety. An unexpected finding from the placebo session data was that, despite increased forehead muscle tension and high self-ratings of distress, chronically anxious subjects showed consistently stable sympathetic activity under resting conditions and mild stress, indicating the existence of a subgroup of generalized anxiety patients with low autonomic reactivity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
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pubmed:issn |
0006-3223
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
16
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1041-50
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:7349618-Adult,
pubmed-meshheading:7349618-Anxiety Disorders,
pubmed-meshheading:7349618-Chronic Disease,
pubmed-meshheading:7349618-Emotions,
pubmed-meshheading:7349618-Female,
pubmed-meshheading:7349618-Humans,
pubmed-meshheading:7349618-Male,
pubmed-meshheading:7349618-Middle Aged,
pubmed-meshheading:7349618-Muscle Contraction,
pubmed-meshheading:7349618-Naloxone,
pubmed-meshheading:7349618-Stress, Physiological,
pubmed-meshheading:7349618-Sympathetic Nervous System
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pubmed:year |
1981
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pubmed:articleTitle |
Effects of naloxone on normals and chronically anxious patients.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't
|