Linked Life Data

7346624

Source:http://linkedlifedata.com/resource/pubmed/id/7346624

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1982-10-12
pubmed:abstractText
A statistical technique for the estimation and differentiation of the operational kinetic parameters for influx of solutes into intestinal rings incubated in vitro is presented. Influx data were fitted to an equation comprising the sum of saturable and diffusional components; the latter is assumed to include entry into the extracellular space, thus avoiding the necessity of indirect assessment with space markers. The estimations are made by non-linear regression analysis on a logarithmic scale. Comparison between data sets is carried out by performing a joint fit under the restriction of parameters common to the two sets. If an F-test reveals no significant loss of information, then the parameter(s) in question do not differ from one set to another. The method is illustrated by an experiment to determine which kinetic parameters for influx of beta-methyl-D-glucoside are altered when sodium is removed from the incubation medium. The results show that the Km is principally affected by this manoeuvre.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0021-7948
pubmed:author
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1011-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
A systematic approach to the analysis of intestinal transport kinetics.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't