Linked Life Data

7335153

Source:http://linkedlifedata.com/resource/pubmed/id/7335153

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1982-5-12
pubmed:abstractText
Total homogenates of astrocytes, neuronal perikarya, and oligodendroglia isolated from rat brain exhibited sialosyltransferase activity in the biosynthesis in vitro of GM3 from lac-cer and CMP-NeuNAc. This activity was highest in neuronal perikarya. In contrast, only oligodendroglia were found to be capable of catalyzing the transfer of NeuNAc from CMP-NeuNAc to gal-cer to form GM4. This activity was about three fold higher in oligodendroglia from 10-day-old rat brain than in those from 60-day-old animals; an intermediate activity was observed in oligodendroglia from 20-day-old rats. Purified preparations of myelin from 14-day-old rat cerebrum, cerebellum, and spinal cord did not show activity in the synthesis of either GM3 or GM4.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0364-3190
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1149-57
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Sialosyltransferase activity and specificity in the biosynthesis in vitro of sialosylgalactosylceramide (GM4) and sialosyllactosylceramide (GM3) by rat astrocytes, neuronal perikarya, and oligodendroglia.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro, Research Support, U.S. Gov't, P.H.S.