Linked Life Data

7333375

Source:http://linkedlifedata.com/resource/pubmed/id/7333375

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1982-5-21
pubmed:abstractText
I.v. administration of prethrombin-1 activates the anticoagulating system but not through the thrombin generation. Perfusion of the rabbit humorally isolated carotid sinus with the prethrombin-1 increases the time of plasma recalcification, total fibrinolytic activity and nonenzymatic fibrinolysis, the effect depending on the prethrombin-1 concentration. The data obtained suggest that the prethrombin-1 is able to activate function of the anticoagulating system interacting with chemoreceptors of the isolated carotid sinus. The prethrombin-1 as well as alpha-thrombin induce similar effects in the anticoagulating system. Therefore the activation of the anticoagulating system is due to areas of chemoreceptors binding in the system and not to presence of the enzyme active center.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0015-329X
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1823-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
[Activation of the anticlotting system by perfusion of the carotid sinus with prethrombin 1 in rabbits].
pubmed:publicationType
Journal Article, English Abstract