Linked Life Data

7331674

Source:http://linkedlifedata.com/resource/pubmed/id/7331674

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-4-12
pubmed:abstractText
The antibody-dependent cell-mediated cytotoxicity and the spontaneous cell-mediated cytotoxicity against Chang liver cells in relation to the levels of circulating K-cells (low affinity E-rosetting cells) were investigated in 23 newly diagnosed insulin-dependent (Type 1) diabetics, and in 17 unaffected islet cell antibody-positive subjects. Antibody-dependent cell-mediated cytotoxicity was significantly increased in those newly diagnosed diabetics with K-cells levels greater than 2 SD above the mean of normal controls (p less than 0.02). A similar but not significant trend was also found in islet cell antibody-positive subjects with raised K-cells. Spontaneous cell-mediated cytotoxicity was not different in any of the groups. These results lend further support to the concept that antibody-dependent lymphocyte cytotoxicity is enhanced in type 1 diabetes at diagnosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0001-5563
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
339-44
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Antibody-dependent and natural killer cytotoxicity in type 1 diabetes.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't