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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1982-4-20
|
| pubmed:abstractText |
From 1960-1980, the technic of abrasive cytologic examination by means of a "balloon catheter" has been used to detect esophageal carcinoma in high-incidence areas with rates of positive diagnosis varying from 87.8% to 91.9%. An application of this technic in mass screenings has led to detection of a large number of very early cases of esophageal carcinoma, of which only about 50% showed positive X-ray findings and 75% showed positive endoscopic findings. Intraluminal staining with toluidine blue through a fiberoptic esophagoscope gave a positive biopsy in 83.9%. In a 16-year period from 1964 through 1979, 237 patients with Stage I esophageal carcinoma underwent surgery. The resectability rate was 100% and the operative mortality 2.5%. Pathologic study of the resected specimens showed carcinoma in situ in 84 cases (35.4%) and early infiltrative carcinoma confined to only the mucosa and submucosa in 153 cases (64.6%). The 5- and 10-year survival rates following resection were 85.9% and 55.6%, respectively. In surgery on 1,647 patients with more advanced carcinoma of the esophagus and who underwent surgery between 1958 and 1979, (resectability rate of 83.4% and a resection mortality of 4.1%), the p-TNM histopathological classification of these patients showed that 72.3% had Stage III and 8.8% had Stage IV diseases, with either extra-esophageal tumor invasion and/or regional lymph node involvements, or distant metastases. The 5-, 10- and 15-year survivals, as calculated by the number of resections were 30.3%, 21.2% and 16.2%, respectively. Analysis showed that prognosis was related to staging of the disease, the extent of tumor invasion, length of the lesion, and the presence or absence of nodal involvement.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0047-1909
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
11
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
399-405
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:7328933-Adult,
pubmed-meshheading:7328933-Aged,
pubmed-meshheading:7328933-Carcinoma,
pubmed-meshheading:7328933-Carcinoma in Situ,
pubmed-meshheading:7328933-Esophageal Neoplasms,
pubmed-meshheading:7328933-Female,
pubmed-meshheading:7328933-Fiber Optic Technology,
pubmed-meshheading:7328933-Humans,
pubmed-meshheading:7328933-Male,
pubmed-meshheading:7328933-Middle Aged,
pubmed-meshheading:7328933-Neoplasm Staging,
pubmed-meshheading:7328933-Prognosis
|
| pubmed:year |
1981
|
| pubmed:articleTitle |
Early detection and surgical treatment of esophageal carcinoma.
|
| pubmed:publicationType |
Journal Article
|