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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
4
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pubmed:dateCreated |
1982-4-12
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|
pubmed:abstractText |
Protoporphyrinogen oxidase activity and ferrochelatase activity have been measured in blood lymphocytes from patients with prophyria variegata, and from some members of the family of one patient; the mean activity of protoporphyrinogen oxidase from patients was about 50% of that in lymphocytes from normal subjects; similar results were obtained from asymptomatic carriers in two generations of the patient's family. This finding confirms that a protoporphyrinogen oxidase decreased activity reflects the primary genetic defect in Porphyria Variegata. Data of ferrochelatase activity have been found usually in the normal range and these results are discussed.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:issn |
0340-6717
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
58
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
425-8
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|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7327566-Female,
pubmed-meshheading:7327566-Ferrochelatase,
pubmed-meshheading:7327566-Flavoproteins,
pubmed-meshheading:7327566-Humans,
pubmed-meshheading:7327566-Lyases,
pubmed-meshheading:7327566-Lymphocytes,
pubmed-meshheading:7327566-Male,
pubmed-meshheading:7327566-Mitochondrial Proteins,
pubmed-meshheading:7327566-Oxidoreductases,
pubmed-meshheading:7327566-Oxidoreductases Acting on CH-CH Group Donors,
pubmed-meshheading:7327566-Pedigree,
pubmed-meshheading:7327566-Porphyrias,
pubmed-meshheading:7327566-Protoporphyrinogen Oxidase,
pubmed-meshheading:7327566-Protoporphyrins
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pubmed:year |
1981
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pubmed:articleTitle |
The inherited enzymatic defect in porphyria variegata.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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