Linked Life Data

7312923

Source:http://linkedlifedata.com/resource/pubmed/id/7312923

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1982-2-12
pubmed:abstractText
A controlled crossover study was carried out on five volunteers to substantiate reported effects of fat intake on the bioavailability of griseofulvin. The urinary excretion of 6-demethylgriseofulvin was monitored for 24 h following the administration of 125-mg griseofulvin tablets in the fasting state and after a fatty diet. Statistical analysis of excretion data indicated a significant increase in both rate and extent of absorption of griseofulvin as a result of fat intake. Excretion rate profiles obtained permitted insight into mechanisms possibly involved in the observed drug-diet interaction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0031-7144
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
692-3
pubmed:dateRevised
2007-1-29
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Influence of high fat diet on GI absorption of griseofulvin tablets in man.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.