Linked Life Data

7312100

Source:http://linkedlifedata.com/resource/pubmed/id/7312100

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1982-2-12
pubmed:abstractText
The performance of male A/J and C57BL/6J mice from three age groups (4, 18, and 24 months) was observed in a battery of tests designed to assess age-related impairments in motor abilities. A/J mice were superior to C57BL/6J mice in tasks requiring upper body strength, such as tests of grip strength and tightrope performance. C57BL/6J mice were superior performers in tasks requiring balance and coordination, such as movement on stationary and rotating rods. In addition, the C57BL/6J strain generally exhibited greater locomotor activity, such as measured in open field and wheel-running tests. Significant age-related deficits were observe among A/J mice in tests of grip strength, balance rod, rotorod, and wheel activity; and among C57BL/6J mice, in balance, rod, tightrope, exploratory activity, and wheel activity tests. Except for scores of exploratory activity (free versus forced exploration), the test measures tended to be uncorrelated; however, the degree and magnitude of intercorrelation among test scores increased with age. The results underscore the need to consider genotype in the assessment of age-related motor impairments in animal models.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0197-4580
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
221-7
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Differential effects of age on motor performance in two mouse strains.
pubmed:publicationType
Journal Article