Linked Life Data

7310108

Source:http://linkedlifedata.com/resource/pubmed/id/7310108

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-2-22
pubmed:abstractText
A substantial level of resistance to a heterologous challenge with Fasciola hepatica was demonstrated in sheep harbouring primary non-patent (two- to three-week-old) and newly patent (seven- to eight-week-old) Schistosoma bovis infections, the liver-fluke burdens being reduced by 70% and 93%, respectively, (p less than 0.01) in these groups compared with that of the challenge control group. The resistance was also reflected in less pronounced F. hepatica-induced liver damage and presumably also in a reduction of the egg-production capacity per established liver-fluke. In contrast, a corresponding heterologous resistance to challenge with F. hepatica could not be demonstrated in sheep harbouring primary 16- to 17-week-old S. bovis infections. Possible, presumably immunological, mechanisms involved in the observed cross-resistance are discussed, as is the possible practical relevance of this cross-resistance phenomenon in attempts to vaccinate sheep against F. hepatica.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0022-149X
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
261-71
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Resistance to Fasciola hepatica in sheep harbouring primary Schistosoma bovis infections.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't