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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
1982-2-12
|
| pubmed:abstractText |
In a prospective study of 178 patients with malignant melanoma, a subset of 33 patients (18.5%) was identified to be at significantly higher risk for developing metastatic disease based on history of cigarette smoking. Patients in this high-risk group (current smokers with a greater than 15 pack-years of smoking history) had two-year disease-free survival rates of 74.2%. versus 92.3% for the remaining patients (p = 0.008). A possible explanation of this phenomenon is that chronic smoking diminishes host defense mechanisms and results in an adverse affect on the biologic behavior of established malignant melanomas.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0148-0812
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
7
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
889-91
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:7309974-Adult,
pubmed-meshheading:7309974-Female,
pubmed-meshheading:7309974-Humans,
pubmed-meshheading:7309974-Male,
pubmed-meshheading:7309974-Melanoma,
pubmed-meshheading:7309974-Middle Aged,
pubmed-meshheading:7309974-Prognosis,
pubmed-meshheading:7309974-Risk,
pubmed-meshheading:7309974-Skin Neoplasms,
pubmed-meshheading:7309974-Smoking
|
| pubmed:year |
1981
|
| pubmed:articleTitle |
Cigarette smoking and malignant melanoma. Prognostic implications.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|