Linked Life Data

7306946

Source:http://linkedlifedata.com/resource/pubmed/id/7306946

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-2-25
pubmed:abstractText
The growth properties of grafts composed of different mixtures of hormone-dependent and independent GR mouse mammary tumor cells were investigated. Grafts containing only hormone-dependent mammary tumor cells yielded tumors in 4--6 weeks in estrone plus progesterone treated castrated mice, but not in castrated mice that were not treated with hormones. Grafts containing only autonomous mammary tumor cells yielded tumors in about 2 weeks in both hormone-treated and untreated castrated mice. Grafts containing mixtures of hormone-dependent and autonomous cells yielded tumors in 2 weeks both in hormone-treated and untreated castrates, even when the grafts contained predominantly hormone-dependent cells (up to 90%). These results indicate that the growth behavior of heterogeneous mammary tumor grafts that contain more than 10% autonomous cells, is essentially determined by these cells. Growth of the autonomous cells is not markedly affected by the presence of hormone-dependent cells in the grafts.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0304-3835
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
71-7
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Outgrowth of grafts containing different ratios of hormone-dependent and independent mouse mammary tumor cells.
pubmed:publicationType
Journal Article