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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1982-2-25
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pubmed:abstractText |
Thirty-seven patients with superficial spreading or nodular melanoma of the head and neck treated with irradiation are reviewed. Twenty-one patients were referred within three months of surgery. Six had an incisional biopsy followed by postoperative irradiation, 4 were locally controlled (1 dying of metastatic melanoma, 2 dying of intercurrent disease and 1 is alive and well), and 2 were not (both dead of melanoma). Fifteen patients had a local excisional biopsy (11 having tumor to the limits of the excision) followed by postoperative irradiation. Fourteen of the 15 had local control (3 had lymph node metastases and died, 3 died of distant metastases from melanoma, 7 are alive and well from 1-14 years following treatment, and one is dead of intercurrent disease), and 1 had a local recurrence and subsequently died of metastatic melanoma. Sixteen patients were irradiated for local and/or regionally recurrent disease following unsuccessful surgery, and only two were successfully controlled by irradiation and are alive and well at four and five years, respectively. Local control was 70% when a dose per fraction of greater than 400 rads was used, compared with 25% when a dose per fraction of less than 400 rads was used. It is concluded that nonlentiginous melanoma of the head and neck is not a radioresistant tumor and that local excision followed by high dose per fraction radiotherapy deserves further study in the management of melanomas of the head and neck.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
|
pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2599-605
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7306920-Adult,
pubmed-meshheading:7306920-Aged,
pubmed-meshheading:7306920-Female,
pubmed-meshheading:7306920-Follow-Up Studies,
pubmed-meshheading:7306920-Head and Neck Neoplasms,
pubmed-meshheading:7306920-Humans,
pubmed-meshheading:7306920-Male,
pubmed-meshheading:7306920-Melanoma,
pubmed-meshheading:7306920-Middle Aged,
pubmed-meshheading:7306920-Prognosis,
pubmed-meshheading:7306920-Radiotherapy Dosage,
pubmed-meshheading:7306920-Skin Neoplasms
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pubmed:year |
1981
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pubmed:articleTitle |
Radiotherapy in nonlentiginous melanoma of the head and neck.
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pubmed:publicationType |
Journal Article,
Case Reports
|