Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1982-1-28
pubmed:abstractText
Neonates from CD-1 mice, which were treated during gestation with 100 mg/kg of 2,4,5-T, were studied from day 1 to 30 postpartum (pp) for effects on cardiac development by determining total cardiac activities and isozyme profiles of LDH and CK. On day 1pp, the total activities and isozyme profiles of LDH of the neonatal hearts were normal. During the developmental period of day 7 through 15, changes were noted in the developmental pattern of LDH isozymes some of which continued to day 30. The CK isozyme profile on day 1pp showed a significant change and changes continued throughout the lactational period. During this period, the normal developmental isozyme patterns of LDH and CK were altered by prenatal exposure to 2,4,5-T suggesting metabolic derangement or pathological changes in the neonatal heart.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0090-4341
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
583-95
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
2,4,5-T effects on cardiac and serum lactic dehydrogenase (LDH) and creatine kinase (CK) isozymes. II. Neonatal enzyme activities and isozyme profiles.
pubmed:publicationType
Journal Article