Linked Life Data

7303820

Source:http://linkedlifedata.com/resource/pubmed/id/7303820

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9-10
pubmed:dateCreated
1982-1-28
pubmed:abstractText
Carefully performed pulse titration of the isolated rat live in the course of continuous erythrocyte free perfusion with small amounts of digitonin causes a short term permeability of liver cell plasma membranes with concomitant short lived release of intracellular low or high molecular compounds such as ATP or lactate dehydrogenase. Gluconeogenesis from lactate being completely inhibited during this period restores within about one minute up to a level that depends on the amount of perfused digitonin. The described experimental model is suggested to be useful for the measurement of cytoplasmic metabolites under physiological conditions. It moreover offers the possibility to import foreign substances into liver cells that normally do not penetrate liver cell plasma membranes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0341-0382
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
880-3
pubmed:dateRevised
2009-6-8
pubmed:meshHeading
pubmed:articleTitle
Titration of rat liver with digitonin: a well defined short term damage of cellular metabolism.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't