Linked Life Data

7302893

Source:http://linkedlifedata.com/resource/pubmed/id/7302893

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-1-20
pubmed:abstractText
The activity of streptokinase (SK) has been examined in a rabbit model of venous thrombosis. Significant thrombolysis was observed at low doses of SK without evidence of systemic activation of the fibrinolytic system. The origin of the specificity of SK-induced fibrinolysis in the rabbit was explored, using a chromogenic substrate coupled assay to measure the enhancement of plasmin generation in the presence of rabbit fibrin. The results obtained suggest that rabbit fibrin influences the fibrinolytic system at three points, viz: the assembly of an activator complex from rabbit plasminogen and SK; the activity of that activator complex towards further rabbit plasminogen; and the activity of the resulting rabbit plasmin in the presence of plasma inhibitors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0340-6245
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
535-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
The thrombolytic activity of streptokinase in the rabbit.
pubmed:publicationType
Journal Article