Linked Life Data

7299625

Source:http://linkedlifedata.com/resource/pubmed/id/7299625

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1982-1-28
pubmed:abstractText
Magnetic guidance of magnetic albumin microsphere for site specific delivery was investigated in mice and rats. After intravenous injection in mice, magnetic microspheres with 1 and 3 micrometer diameter size were localized and retained in the target-site (lung) by application of two permanent magnets to the lungs. Injection into the renal artery in rats also indicated that the 1-micrometer microspheres were concentrated in the kidney by a magnetic field. When the magnets were not applied, however, the microspheres following intravascular injection were concentrated mainly in the liver, regardless of the route of administration. Such preferential localization by magnetic means suggested that magnetic albumin microspheres could become effective drug carriers with site specificity for the delivery of chemotherapeutic agents in cancer therapy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0386-846X
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
624-31
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Biomedical applications of magnetic fluids II. 1) preparation and magnetic guidance of magnetic albumin microsphere for site specific drug delivery in vivo.
pubmed:publicationType
Journal Article