Linked Life Data

7298310

Source:http://linkedlifedata.com/resource/pubmed/id/7298310

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-1-20
pubmed:abstractText
The influence of (+)-catechin (10 mg/100 g daily) and 0-(beta-hydroxyethyl) rutosides (50 mg/100 g daily) on the metabolism and crosslinking of collagen was studied in male albino rats. Compared to controls, the total activity of 3H-hydroxyproline in the dermal soluble collagen did not differ appreciably while the urinary total activity of 3H-hydroxyproline was significantly lowered. When the total activities of both soluble and insoluble collagens are expressed as a percentage of the sum of both, the registered activity was less in soluble and more in salt-insoluble collagen at 12 ans 120 h after the administration of 3H-proline in the treated group. Bioflavonoids were found to decrease the reversibility of neutral salt-soluble collagen gel and solubility of acid-insoluble collagen to denaturing agents. The subunit pattern of neutral salt-soluble collagen on sodium dodecylsulphate polyacrylamide gels revealed a decrease of alpha/beta ratio in bioflavonoids treated animals. The results of the present study indicate that the synthesis of collagen is unaffected, the crosslinking of collagen is promoted and the degradation of soluble collagen is decreased in the bioflavonoids treated groups.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0021-2938
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
259-70
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Influence of bioflavonoids on the metabolism and crosslinking of collagen.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't