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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1982-1-20
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pubmed:abstractText |
Assays for red cell sodium concentration and sodium-dependent lithium efflux were studied from a methodological point of view. The technical errors for sodium concentration--based on concurrent analysis of randomized blind duplicate samples--was 2.5% and for lithium efflux 6.4%. Based on repeated measures in the same individual, the assays were stable over time and reproducible; individual differences at a mean interval of 16 days were not significantly different. A wait of two hours from time of phlebotomy to analysis yielded a slight (3.8%) but significant fall in the sodium concentration; no further change was found at four hours. No change occurred in the lithium efflux over time. A standardized breakfast containing 664 mg sodium did not affect the measurements when fasting and three-hour postprandial levels were compared. The ratios of intra- to inter-individual variance were small--0.04 for red cell sodium concentration and 0.09 for sodium-stimulated lithium efflux. These assays appear to be reproducible and stable and can be applied in large scale field trials.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0009-8981
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
11
|
pubmed:volume |
116
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
319-29
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7296895-Adult,
pubmed-meshheading:7296895-Blood Specimen Collection,
pubmed-meshheading:7296895-Erythrocytes,
pubmed-meshheading:7296895-Female,
pubmed-meshheading:7296895-Humans,
pubmed-meshheading:7296895-Lithium,
pubmed-meshheading:7296895-Male,
pubmed-meshheading:7296895-Sodium,
pubmed-meshheading:7296895-Time Factors,
pubmed-meshheading:7296895-Veins
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pubmed:year |
1981
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pubmed:articleTitle |
Methodological assessment of assays for red cell sodium concentration and sodium-dependent lithium efflux.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|