Linked Life Data

7296391

Source:http://linkedlifedata.com/resource/pubmed/id/7296391

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1982-1-9
pubmed:abstractText
In rats under urethane, multibarrelled microelectrodes were used to record field responses of CA1 hippocampal pyramids evoked by fimbrial-commissural stimulation. A strong potentiation of population spikes could be obtained by either a local release of ACh or by a brief tetanic stimulation of the medial septum (which by itself evoked only minimal field responses of the hippocampus). Both effects were sharply reduced after intravenous injections of large doses of atropine or scopolamine, indicating that the septo-hippocampal innervation is to an important degree cholinergic and muscarinic. However, since dimethylphenylpiperazinium (a nicotinic ganglionic agonist) can also evoke population spikes, a significant though variable component of this cholinergic action may operate via nicotinic receptors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0008-4212
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
911-4
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Septo-hippocampal pathway modulates hippocampal activity by a cholinergic mechanism.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't