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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
14
|
pubmed:dateCreated |
1982-1-20
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pubmed:abstractText |
"In vivo" and "in vitro" action of 2 MPG on lymphocytotoxic activity was evaluated in 22 patients with CAH, 14 were HBsAg positive and 8 were negative. The test was performed with and without 2 MPG in the colture medium, and before and after treatment. HBsAg+ patients received 2 MPG treatment, while HBsAg- ones received immunosoppressive therapy and 4 of these were on 2 MPG treatment as well. Cytotoxic Index was reduced non-significantly by addition of 2 MPG in colture medium in both groups. 2 MPG treatment does not modify cytotoxic activity which is reduced by immunosoppressive therapy. These findings suggest a positive effect of 2 MPG on liver-cell metabolism with an increased resistence of the epatocyte to the "in vitro" lymphocytes aggression. Hence it may be suggested an association treatment with immunosoppressive agents and 2 MPG.
|
pubmed:language |
ita
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0037-8771
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
30
|
pubmed:volume |
57
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1477-83
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:7295410-Amino Acids, Sulfur,
pubmed-meshheading:7295410-Animals,
pubmed-meshheading:7295410-Chronic Disease,
pubmed-meshheading:7295410-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:7295410-Hepatitis B,
pubmed-meshheading:7295410-Hepatitis B Surface Antigens,
pubmed-meshheading:7295410-Humans,
pubmed-meshheading:7295410-Immunosuppressive Agents,
pubmed-meshheading:7295410-Liver,
pubmed-meshheading:7295410-Rabbits,
pubmed-meshheading:7295410-Tiopronin
|
pubmed:year |
1981
|
pubmed:articleTitle |
[Effect of 2 mercaptopropionylglycine on the cytotoxic activity of lymphocytes from patients with chronic active hepatitis against rabbit hepatocytes isolated and cultured in vitro].
|
pubmed:publicationType |
Journal Article,
English Abstract
|