Linked Life Data

7291874

Source:http://linkedlifedata.com/resource/pubmed/id/7291874

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-12-21
pubmed:abstractText
PRL binding capacity to cell membrane fraction was studied in lung tissues obtained from 4 human fetuses or newborn infants. One of the fetuses was a stillborn delivered at 33 weeks of gestation. The newborn infants died for unknown causes within 24 h after birth. The gestational age was 20, 39 and 41 weeks. The cell membrane fraction was prepared by ultracentrifugation. binding capacity and affinity constants were calculated according to athe Scatchard method. No significant specific binding of PRL to lung tissue from the stillborn fetus was observed, while for the other 3 newborn infants the binding capacity was 5.7, 7.4 and 9.6 fmol PRL bound/mg of membrane protein, respectively. The affinity constants were in the order of 10(10) M-1. these preliminary results show that human neonatal lung has receptors for PRL and suggest that PRL itself may be involved in the lung maturation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0390-5748
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
279-82
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Binding of prolactin by fetal human lung cell membrane fractions.
pubmed:publicationType
Journal Article