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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1981-12-21
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pubmed:abstractText |
A noninvasive technique employing photon activation of tissue oxygen in situ and detection of subsequent 15O positron decay was used to study the effects of single-dose 60Co irradiation on capillary blood flow in transplanted rat rhabdomyosarcomas. Tumor blood flow was measured before irradiation with 16.5, 38.5, or 60.5 Gy and at several intervals afterward (0-72 hr.). Pre-irradiation values of volume-averaged blood flow in the tumor ranged from 7 to 44 ml/min./100 g. Several hours after irradiation, blood flow fell by up to 50% for 60.5 Gy and up to 35% for 16.5 Gy. However, 24 hours after irradiation, tumor blood flow had recovered completely in the 16.5-Gy group and substantially in the others. For smaller doses such as the fractions typically employed in radiotherapy, no changes in tumor blood flow were observed.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0033-8419
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
141
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
207-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7291527-Animals,
pubmed-meshheading:7291527-Cobalt Radioisotopes,
pubmed-meshheading:7291527-Female,
pubmed-meshheading:7291527-Half-Life,
pubmed-meshheading:7291527-Male,
pubmed-meshheading:7291527-Neoplasm Transplantation,
pubmed-meshheading:7291527-Oxygen Radioisotopes,
pubmed-meshheading:7291527-Rats,
pubmed-meshheading:7291527-Rats, Inbred Strains,
pubmed-meshheading:7291527-Regional Blood Flow,
pubmed-meshheading:7291527-Rhabdomyosarcoma
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pubmed:year |
1981
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pubmed:articleTitle |
Effects of single-dose irradiation in tumor blood flow studied by 15O decay after proton activation in situ.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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