Linked Life Data

7291290

Source:http://linkedlifedata.com/resource/pubmed/id/7291290

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1981-12-22
pubmed:abstractText
The pharmacokinetic parameters were investigated after a single i.v. application of 50 mg of pethidine (Dolcontral) to women in labour and nonpregnant women. In comparison with the control group (4,2 h) the women in labour had a prolonged biological half life (7,5 h). Furthermore, there was a distinction of distribution parameters. The relation between the average concentration of pethidine in newborn and maternal serum was 0,72. The concentration of pethidine in newborn serum was stated always not as high as the corresponding maternal serum level. There was a significant correlation (r = 0,88) between maternal and fetal pethidine concentration. The half life of pethidine was found to be prolonged (17,2 h) in newborns within two days after birth. The distribution volume and the plasma distribution coefficient were repeatedly enhanced.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0031-7144
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
560-3
pubmed:dateRevised
2007-1-29
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
[The pharmacokinetics of pethidin (Dolcontral) of parturient and their new-borns (author's transl)].
pubmed:publicationType
Journal Article, English Abstract