Linked Life Data

7282806

Source:http://linkedlifedata.com/resource/pubmed/id/7282806

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-11-22
pubmed:abstractText
Amniotic fluid embolism (AFE) has emerged as an important cause of death from legally induced abortion. In the period 1972-1978, 12 probably and three autopsy-confirmed cases of fatal AFE during legally induced abortion were identified in the United States (12% of all deaths from legal abortion). Fourteen deaths from AFE were associated with labor-inducing techniques, and one with hysterotomy. The risk of death appears to be related to gestational age: the death-to-case rate for AFE increases progressively from nil at less than or equal to 12 weeks' gestation to 7.2 deaths per 100,000 abortions at greater than or equal to 21 weeks' gestation. Because treatment is frequently ineffective, prevention of AFE is critical. Performing abortions early in pregnancy and using curettage techniques whenever feasible should reduce the risk of death from this obstetric accident during legally induced abortion.
pubmed:keyword
http://linkedlifedata.com/resource/pubmed/keyword/Abortion, Induced, http://linkedlifedata.com/resource/pubmed/keyword/Abortion, Legal--complications, http://linkedlifedata.com/resource/pubmed/keyword/Acceptor Characteristics, http://linkedlifedata.com/resource/pubmed/keyword/Americas, http://linkedlifedata.com/resource/pubmed/keyword/Blacks, http://linkedlifedata.com/resource/pubmed/keyword/Clinical Research, http://linkedlifedata.com/resource/pubmed/keyword/Cultural Background, http://linkedlifedata.com/resource/pubmed/keyword/Demographic Factors, http://linkedlifedata.com/resource/pubmed/keyword/Developed Countries, http://linkedlifedata.com/resource/pubmed/keyword/Diseases, http://linkedlifedata.com/resource/pubmed/keyword/EMBOLISM, http://linkedlifedata.com/resource/pubmed/keyword/Ethnic Groups, http://linkedlifedata.com/resource/pubmed/keyword/Family Planning, http://linkedlifedata.com/resource/pubmed/keyword/Fertility Control, Postconception, http://linkedlifedata.com/resource/pubmed/keyword/Maternal Age, http://linkedlifedata.com/resource/pubmed/keyword/Maternal Mortality--statistics, http://linkedlifedata.com/resource/pubmed/keyword/Mortality, http://linkedlifedata.com/resource/pubmed/keyword/North America, http://linkedlifedata.com/resource/pubmed/keyword/Northern America, http://linkedlifedata.com/resource/pubmed/keyword/Population, http://linkedlifedata.com/resource/pubmed/keyword/Population Characteristics, http://linkedlifedata.com/resource/pubmed/keyword/Population Dynamics, http://linkedlifedata.com/resource/pubmed/keyword/Pregnancy, http://linkedlifedata.com/resource/pubmed/keyword/Pregnancy, First Trimester, http://linkedlifedata.com/resource/pubmed/keyword/Pregnancy, Second Trimester, http://linkedlifedata.com/resource/pubmed/keyword/Reproduction, http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology, http://linkedlifedata.com/resource/pubmed/keyword/United States, http://linkedlifedata.com/resource/pubmed/keyword/Vascular Diseases, http://linkedlifedata.com/resource/pubmed/keyword/Whites
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0002-9378
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
141
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
257-61
pubmed:dateRevised
2004-11-17
pubmed:otherAbstract
PIP: Amniotic fluid embolism (AFE) has increased in importance as a cause of maternal death. During 1968-75 454 women died of AFE in the U.S., or 9% of all maternal deaths. AFE has recently been found to be an important cause of abortion-related deaths; since 1972 AFE has accounted for 12% of all deaths related to legally induced abortion; the overall estimated death-to-case rate for AFE is 0.2/100.000 legal abortions. 15 cases of fatal AFE associated with legally induced abortion were reported in 1978-79, according to the Center for Disease Controls; 3 of these cases were confirmed by autopsy. Age ranged from 16 to 35 years; 7 patients were white, 6 blacks, and 2 were Asian. Gestational age went from 14 to 35 weeks. 5 women had preexisting conditions; 14 women underwent instillation of hypertonic solution, hyperosmolar urea, or PGF2alpha; 1 woman underwent hysterotomy. All women were in labor when manifestations of AFE became evident; death usually occurred soon after the appearance of signs. Risk of death from AFE seems to increase progressively with advancing gestational age; risk at 21 weeks gestation is about 24 times higher than from abortion at 13-15 weeks' gestation. During the same period of time no deaths were associated with curettage abortions. Estimated death-to-case rate for instillation was not significantly different than for hysterotomy; the estimated death-to-case rate for black women and minority women was 2 times higher than for white women. Age did not make a difference in relationship to death. AFE is caused by the forcing of amniotic fluid into the maternal vascular system during the period of intense uterine contractions. The amount of amniotic fluid is much larger during the second and third trimester of pregnancy; this probably explains the increased risk of death from AFE afer 12 weeks' gestation. Prevention rather than treatment of AFE is of paramount importance. 2 measures may reduce the risk of abortion-related AFE: 1) abortion before the 12-15 week, and 2) curettage at about 13 weeks' gestation. Curettage, presumably by avoiding labor contractions, lowers the risk of AFE.
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Fatal amniotic fluid embolism during legally induced abortion, United States, 1972 to 1978.
pubmed:publicationType
Journal Article