Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8-9
pubmed:dateCreated
1981-11-18
pubmed:abstractText
Fusaric acid (FA) is shown to induce inhibition of noradrenaline and dopamine uptake in synaptosomes from rat hypothalamus and corpus striatum. The basal overflow of noradrenaline and dopamine from "brain stem" and corpus striatum slices is stimulated by FA. While this influence of FA on noradrenaline release is further enhanced by other stimuli (raised K+ concentration or electrical stimulation), no comparable effect can be observed concerning dopamine release. The data show that FA which is known as a potent dopamine-beta-hydroxylase inhibitor of high specificity exerts also marked effect in the central nervous system by interference with other synaptosomal functions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5318
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
935-40
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Interaction at the synaptic level of fusaric acid with neurotransmitters.
pubmed:publicationType
Journal Article, In Vitro