Linked Life Data

7280931

Source:http://linkedlifedata.com/resource/pubmed/id/7280931

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1981-11-22
pubmed:abstractText
The contribution of cytoplasm in the suppression of tumorigenicity was examined in cybrids constructed by fusing whole tumorigenic mouse mammary cells (Balb/c, cell line C2B2 from line MT29240) with enucleated nontumorigenic cells (BALB/c, cell line THOC from clone A31). Chloramphenicol resistance was used as a cytoplasmic marker in selecting the cybrids. Hybrids from parental nonenucleated cells were also isolated and analyzed for the expression of tumorigenicity. A reduction of the tumorigenic capacity in terms of tumor incidence and latency was clearly expressed in most of the cybrid clones studied. In the cybrids, saturation density and colony formation in agarose was also reduced. In most of the hybrid clones studied, a reduction was also observed in the tumorigenic capacity but not in saturation density or anchorage independence.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0098-0366
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
457-71
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
On suppression of tumorigenicity in hybrid and cybrid mouse cells.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't