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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1981-11-18
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pubmed:abstractText |
We report that eseroline, until now thought devoid of any biological action, is a potent antinociceptive agent. Its antinociceptive action is stronger than that of morphine in all tests studied and, though shorter lasting than that of the latter, has a latency of only a few minutes by subcutaneous route. Eseroline, like morphine and enkephalins, inhibits the electrically evoked twitches of the mouse vas deferens and of the guinea-pig ileum. Eseroline, moreover, releases 5-hydroxytryptamine from cat brain cortex in way similar to that of morphine and physostigmine.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
25
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
179-83
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7279315-Analgesics,
pubmed-meshheading:7279315-Animals,
pubmed-meshheading:7279315-Behavior, Animal,
pubmed-meshheading:7279315-Cats,
pubmed-meshheading:7279315-Guinea Pigs,
pubmed-meshheading:7279315-Ileum,
pubmed-meshheading:7279315-Indoles,
pubmed-meshheading:7279315-Male,
pubmed-meshheading:7279315-Mice,
pubmed-meshheading:7279315-Morphine,
pubmed-meshheading:7279315-Muscle Contraction,
pubmed-meshheading:7279315-Rats,
pubmed-meshheading:7279315-Vas Deferens
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pubmed:year |
1981
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pubmed:articleTitle |
Eseroline: a new antinociceptive agent derived from physostigmine with opiate receptor agonist properties. Experimental in vivo and in vitro studies on cats and rodents.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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