Linked Life Data

7276894

Source:http://linkedlifedata.com/resource/pubmed/id/7276894

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-11-22
pubmed:abstractText
Simple amputation of various combinations of hindlimb digits of Notophthalmus viridescens resulted in a variety of abnormal regenerates. The abnormalities included the formation of adventitious digits and branched digits, fusion between digits, and increases and decreases in the normal number of phalanges. The type of abnormality was correlated with the proximal-distal level of amputation and with the identity of the digits removed. These results are discussed in the context of a model for normal digit formation. An important feature of this model is that the normal regeneration of separate digits is dependent upon precise and orderly interactions between different parts of the limb circumference. In the experiments we report, the disruption of these orderly interactions leads to a variety of abnormalities. In addition, the model for digit formation presented here is discussed in light of its implications for evolutionary trends in the tetrapod limb.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0022-104X
pubmed:author
pubmed:issnType
Print
pubmed:volume
216
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
423-33
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Studies of digit regeneration and their implications for theories of development and evolution of vertebrate limbs.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.