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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1981-11-22
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pubmed:abstractText |
Afternoon but not morning injections of melatonin (Mel) resulted in significant 68, 50 and 20% reductions in seminal vesicle, ventral prostate and testicular weights, respectively, as compared with underfed controls. As in the animals injected in the morning, reproductive organ weights in underfed-pinealectomized rats were unaffected by afternoon injections of Mel. Both pituitary and serum prolactin levels were significantly depressed in underfed rats receiving Mel in the afternoon; however, Mel was ineffective when given either in the morning or to pinealectomized rats. These data indicate that there is a diurnal rhythm of sensitivity to Mel in undernourished rats which is abolished by pinealectomy.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0301-0163
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
104-13
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7275001-Animals,
pubmed-meshheading:7275001-Circadian Rhythm,
pubmed-meshheading:7275001-Fasting,
pubmed-meshheading:7275001-Male,
pubmed-meshheading:7275001-Melatonin,
pubmed-meshheading:7275001-Pineal Gland,
pubmed-meshheading:7275001-Pituitary Gland,
pubmed-meshheading:7275001-Prolactin,
pubmed-meshheading:7275001-Prostate,
pubmed-meshheading:7275001-Rats,
pubmed-meshheading:7275001-Rats, Inbred Strains,
pubmed-meshheading:7275001-Seminal Vesicles,
pubmed-meshheading:7275001-Testis
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pubmed:year |
1981
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pubmed:articleTitle |
Nutritional status, time of day and pinealectomy: factors influencing the sensitivity of the neuroendocrine-reproductive axis of the rat to melatonin.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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