Linked Life Data

7274089

Source:http://linkedlifedata.com/resource/pubmed/id/7274089

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-11-22
pubmed:abstractText
The glycerophospholipid (GPL) content and the acyl group compositions of the ethanolamine and choline glycerophospholipids (EGP, CGP) of the isolated brain capillary cell fractions of the developing rat have been determined. The proportion of EGP/GPL increases during development, whilst CGP/GPL declines: consequently EGP/CGP increases with age. The acyl group compositions of the plasmenylethanolamine (P-GPE) and the diacyl glycerophosphocholine (D-GPC) also change during development, the proportions of saturated fatty acids (SFAs) declining and n-6 groups rising. The rates of accumulation of individual acyl groups of EGP and CGP are highest between the ages of 15 and 20 days; particularly evident is the increase in the medium chain SFAs: 16:0 and 18:0, the monoene 18:1n-9 (oleic acid) and the major-occurring polyunsaturated fatty acid, arachidonic acid, in these GPLs. These changes are compared with those of the liver where the proportion of EGP/CGP remains constant and the acyl group compositions are relatively unchanged during development. Consequently, the rates of accumulation of individual acyl groups of EGP and CGP in liver remain constant or rise slightly during this age period. These results are compared with existing accounts of the desaturation capabilities of brain and liver with age.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0378-5866
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
201-10
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Glycerophospholipids and acyl group changes in rat brain capillary endothelial cell fraction and the liver during development.
pubmed:publicationType
Journal Article