rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
1981-10-25
|
pubmed:abstractText |
The relative contributions of parenchymal cells and non-parenchymal (sinusoidal) cells to the in vivo hepatic uptake of chylomicron remnants was measured 30 min after intravenous injection into rats. The chylomicron remnants were labeled with [3H]leucine, which was almost exclusively present in apolipoprotein B. The isolated non-parenchymal cells (a mixture of Kupffer cells and endothelial cells) contained 6.7 times more apolipoprotein B radioactivity per mg cell protein than the isolated parenchymal cells. It was calculated that the contributions of non-parenchymal and parenchymal liver cells to the total hepatic uptake of chylomicron remnants are 35% and 65%, respectively.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0026-0495
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
792-7
|
pubmed:dateRevised |
2003-11-14
|
pubmed:meshHeading |
pubmed-meshheading:7266372-Adenine,
pubmed-meshheading:7266372-Animals,
pubmed-meshheading:7266372-Apolipoproteins,
pubmed-meshheading:7266372-Apolipoproteins B,
pubmed-meshheading:7266372-Chylomicrons,
pubmed-meshheading:7266372-Leucine,
pubmed-meshheading:7266372-Liver,
pubmed-meshheading:7266372-Lymph,
pubmed-meshheading:7266372-Male,
pubmed-meshheading:7266372-Methods,
pubmed-meshheading:7266372-Rats,
pubmed-meshheading:7266372-Tritium
|
pubmed:year |
1981
|
pubmed:articleTitle |
Relative contributions of parenchymal and non-parenchymal (sinusoidal) liver cells in the uptake of chylomicron remnants.
|
pubmed:publicationType |
Journal Article
|