Linked Life Data

7263373

Source:http://linkedlifedata.com/resource/pubmed/id/7263373

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1981-10-25
pubmed:abstractText
To evaluate interactions between increased permeability of the pulmonary vasculature and increased hydrostatic pressure on lung fluid flux, we measured water and blood contents of five equally thick slices of in situ perfused dogs' lungs that had been vertically suspended and, after experimental manipulations, rapidly frozen. Measurements were made under four sets of conditions (4 dogs each): 1) control; 2) increased left atrial pressure (Pla), 25 cmH2O relative to the bottom of the lung; 3) oleic acid; and 4) oleic acid and increased Pla. Significant interactions on lung water content were found between 1) oleic acid and increased Pla (P less than 0.005) and 2) oleic acid and height of the slice of lung (P less than 0.003). Blood content was significantly affected by interactions between 1) oleic acid and height of the lung slice (P less than 0.001) and 2) increased Pla and height of the lung slice (P less than 0.001). We conclude that there are significant interactions between increased permeability and hydrostatic pressure that affect regional lung water content and intrapulmonary distribution of blood.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0161-7567
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
905-11
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Interactions between permeability and hydrostatic pressure in perfused dogs' lungs.
pubmed:publicationType
Journal Article, In Vitro, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't