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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5-6
|
pubmed:dateCreated |
1981-9-15
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pubmed:abstractText |
Formation of nitrosamines, after absorption of nitrite and secondary or tertiary amines in the gastro-intestinal tract, is used as a chemical test of carcinogenicity in the Rat. We have confirmed the carcinogenic power of a tertiary amine association: aminophenazone, and sodium nitrite giving dimethyl-nitrosamine in Sprague Dawley rats: both substances are administered at low and high concentrations in drinking water. We have studied simultaneously, the propyphenazone/sodium nitrite association in the same experimental conditions without carcinogenic power: --treatment duration: thirty weeks, --study duration: two years with observation of carcinogenic reactions, --verification of data: control and substances given independently.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Aminopyrine,
http://linkedlifedata.com/resource/pubmed/chemical/Antipyrine,
http://linkedlifedata.com/resource/pubmed/chemical/Carcinogens,
http://linkedlifedata.com/resource/pubmed/chemical/Nitrites,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium Nitrite,
http://linkedlifedata.com/resource/pubmed/chemical/propyphenazone
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pubmed:status |
MEDLINE
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pubmed:issn |
0003-4037
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
34
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1133-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7258913-Aminopyrine,
pubmed-meshheading:7258913-Animals,
pubmed-meshheading:7258913-Antipyrine,
pubmed-meshheading:7258913-Carcinogens,
pubmed-meshheading:7258913-Drug Interactions,
pubmed-meshheading:7258913-Female,
pubmed-meshheading:7258913-Male,
pubmed-meshheading:7258913-Neoplasms, Experimental,
pubmed-meshheading:7258913-Nitrites,
pubmed-meshheading:7258913-Rats,
pubmed-meshheading:7258913-Sodium Nitrite
|
pubmed:year |
1980
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pubmed:articleTitle |
[Comparison of the effects of absorption of aminophenazone or propyphenazone combined with sodium nitrite on the incidence and early appearance of tumors in the rat].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|