Linked Life Data

7254767

Source:http://linkedlifedata.com/resource/pubmed/id/7254767

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-9-25
pubmed:abstractText
A study of the lenses of CatFr/+ and +/+ mice at different stages of embryonic and postembryonic development by means of electron and light microscopy has shown that the effect of CatFr gene single dose is characterized by a more rapid denucleation of lens fibers, as compared with the normal development. Defects of the nuclear envelope structure, similar with those described earlier for homozygotes, were observed in the developing lenses of heterozygotes. In CatFr/+ mice, unlike in homozygotes, the nuclei of primary lens fibers are not practically affected but those of secondary fibers are destroyed, thus leading to the lysis of these fibers and the development of cataract. The expression of CatFr gene in heterozygotes is due to additive interaction of its effects and "denucleation" process.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0475-1450
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
298-305
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
[Effects of a single dose of the mutant gene CatFr in mouse ontogeny].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract