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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1981-9-15
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pubmed:abstractText |
The rad alleles of 18 unlinked genes of S. pombe were tested for their level of spontaneous meiotic, spontaneous mitotic and UV-induced mitotic recombination in the ade7-50 x ade7-152 interval. The effects of these rad alleles on meiosis and cell morphology were also studied. None of these mutants showed a clear-cut reduction of spontaneous recombination rates, no matter whether they had lost or retained a caffeine-sensitive repair of UV-induced lesions, which has previously been interpreted as a recombinational pathway of DNA repair (Fabre, 1972a; Gentner, 1977; Gentner et al., 1978). rad1-1 was the only mutant with a reduced frequency of UV-induced recombination. Some mutants displayed an increased frequency of mitotic recombination, either spontaneously (rad 15-P, rad 21-45), UV-induced (rad8-190) or both (rad2-44). Previous hypothesis on the contribution of recombination to DNA repair in S. pombe are reconsidered in the light of these data.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0027-5107
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
37-48
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7254221-Alleles,
pubmed-meshheading:7254221-Ascomycota,
pubmed-meshheading:7254221-DNA Repair,
pubmed-meshheading:7254221-Mutation,
pubmed-meshheading:7254221-Phenotype,
pubmed-meshheading:7254221-Radiation Tolerance,
pubmed-meshheading:7254221-Recombination, Genetic,
pubmed-meshheading:7254221-Schizosaccharomyces,
pubmed-meshheading:7254221-Ultraviolet Rays
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pubmed:year |
1981
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pubmed:articleTitle |
Spontaneous and UV-induced recombination in radiation-sensitive mutants of Schizosaccharomyces pombe.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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