Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1981-9-15
pubmed:abstractText
A double isotope methodology was used to assess the effect of methylxanthine administration on membrane protein synthesis in developing rat brain. Rat pups were given either aminophylline, theophylline, or caffeine in a dosage of 40 mg/kg or 80 mg/kg daily from the second postnatal day through 20 days of age. Results show depressed myelin protein synthesis at 21.24 days by theophylline (80 mg/kg) and caffeine (40 and 80 mg/kg). Synthesis was essentially normal at 27-28 days of age, indicating a possible delay in development followed by a 'catch-up' phenomenon.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
213
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
476-80
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
A possible effect of the methylxanthines caffeine, theophylline and aminophylline on postnatal myelination of the rat brain.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.