Linked Life Data

7247787

Source:http://linkedlifedata.com/resource/pubmed/id/7247787

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1981-8-27
pubmed:abstractText
A patient had an ischemic infarction of the right medial thalamus, with a resultant contralateral neglect syndrome. We propose that the medial thalamic nuclei, particularly centromedian and parafascicularis (CMPF), are normally involved in the arousal-activation process by which an organism can be aroused by and respond to novel or important stimuli. Specifically, we propose that (1) the mesencephalic reticular formation subserves tonic arousal to novel or painful stimuli by inhibiting the nucleus reticularis thalami (NR) and (2) that selective attention is mediated by cortical input to NR. The CMPF is closely associated with motor systems (basal ganglia, ventrolateral nucleus of the thalamus [VL], and frontal lobes). A pathway involving CMPF, the frontal cortex, and the portion of NR associated with VL may be important in preparing the tonically aroused organism for action. Unilateral lesions of CMPF therefore induce an asymmetric hypokinesia, and bilateral lesions may induce akinetic mutism.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0003-9942
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
501-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Thalamic neglect. Possible role of the medial thalamus and nucleus reticularis in behavior.
pubmed:publicationType
Journal Article, Case Reports