Linked Life Data

7240777

Source:http://linkedlifedata.com/resource/pubmed/id/7240777

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-8-10
pubmed:abstractText
Radioimmunological estimation of prostatic acid phosphatase was carried out in 72 reference subjects, 46 patients with benign prostatic hypertrophy, 106 patients with untreated prostatic carcinoma and 25 patients with a carcinoma of some other origin. The mean concentration in non-acidified serum was 1.3 +/- 0.4 (M +/- SD) ng/ml for the reference group and 1.6 +/- 0.8 ng/ml for the benign hypertrophy group. The upper limit of discriminatory values for the diagnosis of prostatic carcinoma was fixed at 3 ng/ml. Taking this value, the overall percentage of positive results for carcinoma of the prostate was 61% (65/106). The number of cases with a value greater than 3 ng/ml was 3/18 (17%) for stage A, 8/27 (30%) for stage B, 7/13 (54%) for stage C and 47/48 (98%) for stage D. 8% (2/25) of carcinomas of another origin gave a positive result. The results of estimation using the radioimmunological technique were compared with those obtained by the measurement of enzyme activity using para nitro-phenyl phosphate as a substrate in 34 untreated prostatic carcinomas (all stages mixed together). When measurements by both techniques were carried out under the same ideal conditions using fresh sera as soon as possible after the blood was drawn, the result was abnormal in 10 cases out of 12 (83%) for the radioimmunological method and in 8 cases out of 12 (67%) for the measurement of enzyme activity. By contrast, under routine conditions, the positive percentage figures were 77% (17/22) for the radioimmunological technique and only 36% (8/22) for the measurement of enzyme activity. It would thus appear that radioimmunological measurement is more reliable than the measurement of enzyme activity.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0248-0018
pubmed:author
pubmed:issnType
Print
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
169-73
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
[The diagnostic value of the radioimmunological estimation of prostatic acid phosphatase. Comparative value of the measurement of enzyme activity (author's transl)].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract