Linked Life Data

7239848

Source:http://linkedlifedata.com/resource/pubmed/id/7239848

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1981-8-10
pubmed:abstractText
The present studies suggest that polymorphonuclear leukocytes (PMNs) play an essential role in the development of corneal infiltrates in stromal herpes virus (HSV) keratitis. Corneal infiltration was seen rarely in herpes-infected animals treated with anti-PMN serum or with chemotherapy to reduce the numbers of circulating PMNs. By contrast, at least two thirds of the control animals with intact PMNs and infected with herpes virus developed stromal infiltrates. Host complement was localized with HSV antigen and rabbit gamma globulin along with inflammatory cells in the corneas of animals with stromal infiltrates. In the absence of PMN infiltrates, neither complement nor a significant amount of gamma globulin was localized in the corneal stroma. In the PMN-depleted animals, only viral antigen was detected in the stromal keratocytes.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0146-0404
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
784-98
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Immunopathogenesis of corneal inflammation in herpes simplex virus stromal keratitis: role of the polymorphonuclear leukocyte.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't