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Fat necrosis in the mesentery is an unusual complication of an adjacent inflammatory process. This report demonstrates a case of fat necrosis resulting in multiple irregularly firm masses measuring up to 4.5 cm. in diameter which produced extrinsic pressure on the cecum and ascending colon, simulating a carcinoma radiographically and at surgery. The fat necrosis was caused by chronic appendicitis in association with pylephlebitis.
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