Linked Life Data

7234441

Source:http://linkedlifedata.com/resource/pubmed/id/7234441

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1981-7-9
pubmed:abstractText
Guinea-pig and rabbit urinary bladders were fixed in glutaraldehyde at different volumes. Strips were dissected out, embedded and cut for phase contrast and electron microscopy. Muscle wall thickness decreased with increased bladder volume as did the radial number of muscle cells. Cell length, measured by a morphometric method increased linearly with bladder radius, indicating that no slippage between the muscle cells occurred. Number of cells per mm2 cross sectional area increased linearly with bladder radius. Volume-active force relations were obtained by pelvic nerve stimulations of guinea pig bladders filled to different volumes. Maximum pressure was obtained at 0.15 ml bladder volume, and maximum wall tension at a volume of 2.5 ml which corresponds to a cell length of 400 micrometers and a cell packing density of about 107 000 x mm-2. Estimation of the length-active tension curve for the average muscle cell in the guinea-pig bladder indicated a maximum active force of 5.5 microN/cell. Maximum active force per cm2 muscle bundle was calculated to be about 59 N. No compensation for extracellular space and nonmuscular tissue within the muscle bundle was made.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0001-6772
pubmed:author
pubmed:issnType
Print
pubmed:volume
110
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
357-65
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Relation between cell length and force production in urinary bladder smooth muscle.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't