Linked Life Data

7230721

Source:http://linkedlifedata.com/resource/pubmed/id/7230721

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1981-7-20
pubmed:abstractText
A girl of German origin with severe congenital hemolytic anemia was found to have overhydrated erythrocytes with markedly increased sodium and reduced potassium concentrations. The cells were stomatocytic with increased osmotic fragility and autohemolysis. Their excessively increased energy production was mainly used for active cation transport. The cells were highly vulnerable to metabolic depletion. Their normal deformability was reduced rapidly during deprivation of glucose. In acidic, hypoglycemic environment of the splenic pulp the cells become swollen and lysed. After splenectomy anemia improved though increased hemolysis persisted.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0023-2173
pubmed:author
pubmed:issnType
Print
pubmed:day
16
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
173-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Role of the spleen in congenital stomatocytosis associated with high sodium-low potassium erythrocytes.
pubmed:publicationType
Journal Article, Case Reports, Research Support, Non-U.S. Gov't