Linked Life Data

7229514

Source:http://linkedlifedata.com/resource/pubmed/id/7229514

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1981-7-20
pubmed:abstractText
IgM RF is known to react with many species of IgG. This study examined nine species of IgG to determine which was the most sensitive and specific to detect IgG RF by radioimmunoassay. For 19 IgM RF-positive sera, horse IgG was significantly more sensitive than all IgG preparations tested except rabbit IgG. The IgG used include sheep, swine, goat, bovine, and chicken as well as human and baboon Fc. For 22 IgM RF-negative sera from patients with rheumatoid arthritis, only one was positive for IgG RF with rabbit IgG, whereas five were positive with horse IgG. Analysis after preparative ultracentrifugation of a variety of sera positive and negative for IgM RF indicated that horse IgG was more sensitive, whereas rabbit IgG was more specific for the detection of IgG RF by our radioimmunoassay. IgM RF, on the other hand, was more sensitively detected by human Fc than by any preparation other than whole human IgG.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0022-2143
pubmed:author
pubmed:issnType
Print
pubmed:volume
97
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
842-53
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
IgG rheumatoid factor: analysis of various species of IgG for detection by radioimmunoassay.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't